SLU-PP-332

Overview

  • CAS Number: 303760-60-3
  • Chemical Formula: C18H14N2O2
  • Molecular Weight: 290.32 g/mol
  • Purity: ≥98%

IUPAC Name: 4-Hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide

Pharmacological Profile
SLU-PP-332 is a potent pan-estrogen related receptor agonist (ERRα, ERRβ, ERRγ) with nanomolar activity. Plasma concentrations in the order of tens of ng/mL are sufficient for full receptor activation.
Dose Rationale
The optimal range is 0.2–1 mg per unit dose. This dosage is sufficient thanks to its transcriptional amplification mechanism and both oral and sublingual bioavailability. Comparisons with levothyroxine, SERMs, and PPAR ligands confirm the low-dose efficacy.
Applications in Research
The compound is used in research to study metabolism, mitochondrial biogenesis, and transcriptional regulation. It is intended exclusively for qualified laboratories and is not suitable for human or veterinary use.
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Disclaimer: For laboratory research only. Not for human consumption. Not for veterinary use.