What is SLU-PP-332?
SLU-PP-332 is a research-grade metabolic modulator designed to boost energy expenditure—mimicking the effects of intense cardio, even on rest days. Originating from a decade of work at Washington University School of Medicine, it targets the ERR receptor family to enhance mitochondrial output, fat oxidation, and endurance.
How it Works
- Pan-ERR Activation: Targets ERRα (EC50: 98 nM), ERRβ (230 nM), and ERRγ (430 nM).
- Exercise-Mimicking Action: Triggers cellular programs similar to high-intensity training or intermittent fasting.
- Cardio-Metabolic Benefits: Enhances mitochondrial function across muscle and heart tissues.
Key Benefits
- Increases daily energy burn
- Reduces fat cell size and fat mass
- Improves insulin sensitivity and lipid levels
- Preserves muscle during weight loss
- Boosts heart performance in preclinical models
Precision Dosage & Transparency
Each 5 mL vial contains exactly 6 mg of SLU-PP-332 (1.2 mg/mL):
- Each drop (~20 µg) enables ultra-precise control.
- Every label includes a QR code linking to certified lab analysis.
Scientific Foundations
- C. Billon et al., “Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity,” ACS Chem. Biol. 18, 756 (2023).
- W. Xu et al., “Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function,” Circulation 149, 227 (2024).
RESEARCH USE ONLY — NOT FOR HUMAN CONSUMPTION. For laboratory research purposes only. Not for medical, veterinary, or household use.